HODGKIN LYMPHOMA (HL)
Hodgkin’s lymphoma is a monoclonal (excessive proliferation of one type) cancer of lymphoid tissue cells and a disorder with high treatment rates. It is also called lymphatic cancer, which is more commonly known. Biological and clinical studies conducted on this disease are divided into 2 main categories: classic Hodgkin’s lymphoma and nodular lymphocyte-predisposing hodgkin’s lymphoma of the disease. In pathological examinations of Hodgkin’s lymphoma, “Reed-Sternberg cells” originating from B cells, which are characteristic, are detected.Classic hodgkin’s lymphoma is a type of hodgkin’s lymphoma that is detected in about 95% of this type of lymph cancer. These cancers usually tend to start in the lymph nodes in the cervical (neck) region. Although the underlying cause of the disease is not known for sure, there is an increased risk of developing Hodgkin’s lymphoma in people infected with the Epstein Barr virus, autoimmune diseases, and immunocompromised people. Hodgkin lymphoma, which usually occurs in the young adult age group, has an approximately 80% cure rate.
How is Hodgkin’s lymphoma (lymph cancer) treated?
The treatment of lymphatic cancer is performed by oncologists in hematology-oncology services. With modern chemotherapy, lymphoma patients can be cured by 70-80%. Factors that affect the course of the disease are the stage of the disease, whether the patient responds to treatment, the type of lymphoma, recurrence of lymphoma, whether there is diabetes or kidney disease with it.
Chemotherapy drugs used in the treatment of lymphoma cancer can be administered alone or in various combinations. These drugs are used to eliminate cancer cells and prevent their proliferation. Chemotherapy drugs used to treat lymphoma are usually given to patients through a large venous vein located in the chest area. There are 3 basic chemotherapy regimens used for Hodgkin’s lymphoma.
In case of recurrence of lymphoma, bone marrow and stem cell transplantation are also often resorted to. In case of recurrence of the disease, high doses of chemotherapy should be administered. Since this will damage the bone marrow, the bone marrow taken from the patient before chemotherapy is transplanted back to the patient after chemotherapy. In patients with bone marrow involvement, bone marrow transplantation can also be performed from family relatives.
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